The development of new bone can be a multistep process: first, stem cells differentiate into cartilage cells. Next, the cartilage cells become bone cells. But that’s not all: the cells must experience some mechanical stresses during the transformation in order to transform efficiently from stem cells to bone cells.
From https://jamesjohnson10.blogspot.com/2019/08/addition-of-growth-factors-to-unique.html
from
https://jamesjohnson10.wordpress.com/2019/08/29/addition-of-growth-factors-to-unique-system-helps-new-bone-formation/
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